Author

Joseph D. Long

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Beate IllekiD· 1 shared Brigitte N. GompertsiD· 1 shared Colin J. JuettiD· 1 shared Donald B. KohniD· 1 shared Emily C. DugganiD· 1 shared Lindsay E. LathropiD· 1 shared Neil Fernandes· 1 shared Paul George AyoubiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Beate IllekORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Investigation of Double-Stranded DNA Donors and CRISPR-Cas9 RNP for Universal Correction of Mutations Causing Cystic Fibrosis in Human Airway Cells

Vrishti Sinha, Paul George Ayoub, Colin J. Juett, Lindsay E. Lathrop, Ruth A. Foley, Ruby A. Sims, Joseph D. Long, Emily C. Duggan, Neil Fernandes, Beate Illek, Brigitte N. Gomperts, Steven John Jonas, Donald B. Kohn

This study demonstrates that low levels of CFTR integration can restore chloride ion currents in human airway cells using optimized nonviral CRISPR-Cas9 RNP and double-stranded DNA donors.

bioRxiv · Sep 21, 2025 · PreprintGenetics