Chromatin remodeling of histone H3 variants underlies epigenetic inheritance of DNA methylation
Seung Cho Lee, Dexter W. Adams, Jonathan J. Ipsaro, Jonathan Cahn, Jason S. Lynn, Hyun Soo Kim, Benjamin Berube, Viktoria Major, Joseph P. Calarco, Chantal LeBlanc, Sonali Bhattacharjee, Umamaheswari Ramu, Daniel Grimanelli, Yannick Jacob, Philipp Voigt, , Robert A. Martienssen
The paper shows that DDM1 remodels histone H3 variants to facilitate epigenetic inheritance of DNA methylation by interacting with specific histone modifications and variants.
Cell · Aug 28, 2023Peer-reviewedMolecular Biology