Molecular BiologyNature GeneticsPeer-reviewed
Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas
Jessica D. St. Laurent, Grace Dydian Xu, Alexander Wang Ying…·Cigall Kadoch
This study identifies shifted mSWI/SNF subcomplex stoichiometry in DDEC/UEC cancers and shows that SMARCA4/2 inhibitors reduce tumor growth and synergize with chemotherapy.
4 citations