A bacterial NLR-related protein senses distinct phage triggers through a single interface
Laurel K. Robbins, Emily M. Kibby, Amar Deep, Nathan K. Min, Lindsay A. Whalen, Layla D. Borja Najera, Toni A. Nagy, Layla R. Freeborn, Emily G. Armbruster, Joseph Pogliano, Kevin D. Corbett, Aaron T. Whiteley
This study identifies a bacterial NLR-related protein that detects phage infection through a conserved interface, triggering programmed cell death to limit viral spread.
bioRxiv · Dec 17, 2024 · PreprintMicrobiology