Author

Layla R. Freeborn

University of Colorado BoulderORCID 0000-0002-3299-4666Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aaron T. WhiteleyiD· 1 shared Adam M. M. StuckertiD· 1 shared Alex GuzmániD· 1 shared Amar DeepiD· 1 shared Andrew H. VaughniD· 1 shared Corinne L. Richards‐ZawackiiD· 1 shared Diana Aguilar‐GómeziD· 1 shared Emily G. ArmbrusteriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Aaron T. WhiteleyORCID

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2 papers

Recent·Most cited

Evolution and Diversification of the Aposematic Poison Frog, Oophaga pumilio, in Bocas del Toro

Diana Aguilar‐Gómez, Layla R. Freeborn, Lin Yuan, Lydia L. Smith, Alex Guzmán, Andrew H. Vaughn, Emma Steigerwald, Adam M. M. Stuckert, Yusan Yang, Tyler P. Linderoth, Matthew D. MacManes, Kevin J. McGraw, Corinne L. Richards‐Zawacki, Rasmus Nielsen

This study identifies genetic factors underlying color and pattern variation in Oophaga pumilio frogs from Bocas del Toro, finding key genes involved in different polymorphisms and evidence of selective sweeps.

Current Biology · Feb 18, 2026Peer-reviewedEvolutionary Biology

A bacterial NLR-related protein senses distinct phage triggers through a single interface

Laurel K. Robbins, Emily M. Kibby, Amar Deep, Nathan K. Min, Lindsay A. Whalen, Layla D. Borja Najera, Toni A. Nagy, Layla R. Freeborn, Emily G. Armbruster, Joseph Pogliano, Kevin D. Corbett, Aaron T. Whiteley

This study identifies a bacterial NLR-related protein that detects phage infection through a conserved interface, triggering programmed cell death to limit viral spread.

bioRxiv · Dec 17, 2024 · PreprintMicrobiology