Author

Josh Wu

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Anna-Lena B.G. VigiliD· 1 shared Ayaha ItokawaiD· 1 shared Brock J. McKinneyiD· 1 shared Douglas B. FoxiD· 1 shared James V. AlvareziD· 1 shared Kelley R. McCutcheoniD· 1 shared Lucas B. SullivaniD· 1 shared Oliver J. NewsomiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Anna-Lena B.G. VigilORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Recurrent Breast Cancer Cells Depend on De novo Pyrimidine Biosynthesis to Suppress Ferroptosis

Kelley R. McCutcheon, Josh Wu, Yasemin Ceyhan Ozdemir, Brock J. McKinney, Sharan Srinivasan, Ayaha Itokawa, Oliver J. Newsom, Anna-Lena B.G. Vigil, Douglas B. Fox, Lucas B. Sullivan, James V. Alvarez

This study identifies de novo pyrimidine synthesis as a metabolic vulnerability in recurrent breast cancer cells that suppresses ferroptosis, with DHODH inhibition selectively targeting these cells.

bioRxiv · Nov 17, 2025 · PreprintCancer Biology