Kelley R. McCutcheon

This study identifies de novo pyrimidine synthesis as a metabolic vulnerability in recurrent breast cancer cells that suppresses ferroptosis, with DHODH inhibition selectively targeting these cells.

This study shows that both PFOA and Gen X, two PFAS compounds, are teratogenic to sea urchin embryos, with Gen X causing more severe developmental effects.

ICAT improves identification of cell states after perturbations in single-cell RNA sequencing by using self-supervised feature weighting and control-guided clustering.