Corticostriatal Maldevelopment in the R6/2 Mouse Model of Juvenile Huntington Disease
Carlos Cepeda, Sandra M. Holley, Joshua Barry, Katerina D. Oikonomou, Vannah-Wila Yazon, Allison Peng, Deneen Argueta, Michael Levine
This paper examines corticostriatal development in the R6/2 mouse model of juvenile Huntington disease, finding early cortical malformations and transient synaptic deficits that normalize by postnatal day 21.
Neurobiology of Disease · Dec 5, 2024Peer-reviewedNeuroscience