Author

Joshua L. Margolis

University of Michigan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Andrew M. TidballiD· 2 shared J. Clayton Walker· 2 shared Jack M. ParentiD· 2 shared Emma G. Kilbane· 1 shared Geoffrey G. MurphyiD· 1 shared Jun Z. LiiD· 1 shared Lori L. IsomiD· 1 shared Luis F. Lopez‐SantiagoiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

Andrew M. TidballORCID

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2 papers

Recent·Most cited

Self-organizing Single-Rosette Brain Organoids from Human Pluripotent Stem Cells

Andrew M. Tidball, Wei Niu, Qianyi Ma, Taylor N. Takla, J. Clayton Walker, Joshua L. Margolis, Sandra P. Mojica-Perez, Roksolana Sudyk, Shannon J. Moore, Ravi Chopra, Vikram G. Shakkottai, Geoffrey G. Murphy, Jun Z. Li, Jack M. Parent

The paper describes a method to generate reproducible single-rosette brain organoids from human pluripotent stem cells and uses them to study structural phenotypes in neurodevelopmental disorders.

bioRxiv · Feb 28, 2022 · PreprintNeuroscience

Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons

Andrew M. Tidball, Luis F. Lopez‐Santiago, Yukun Yuan, Trevor W. Glenn, Joshua L. Margolis, J. Clayton Walker, Emma G. Kilbane, Lori L. Isom, Jack M. Parent

This study uses patient-derived iPSC neurons to show variant-specific changes in sodium currents in SCN8A-EIEE13, identifying altered persistent and resurgent INa and potential therapeutic responses.

bioRxiv · Jan 16, 2020 · PreprintNeuroscience