NeurosciencebioRxivPreprint
Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons
Andrew M. Tidball, Luis F. Lopez‐Santiago, Yukun Yuan…·Jack M. Parent
This study uses patient-derived iPSC neurons to show variant-specific changes in sodium currents in SCN8A-EIEE13, identifying altered persistent and resurgent INa and potential therapeutic responses.
DOI 10.1101/2020.01.16.909192