Author

Joshua Li

National Institute of Neurological Disorders and Stroke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Adrian M. Eiden· 1 shared Alan P. KoretskyiD· 1 shared Amreen MughaliD· 1 shared Boxue TianiD· 1 shared Deisha Paliwal· 1 shared Dong Gun Oh· 1 shared Eugenia Flores FigueroaiD· 1 shared Faiyaz NottaiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Adrian M. Eiden

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Electro-Calcium uncoupling precedes neurodegeneration in Alzheimers disease

Hwoi Chan Kwon, Adrian M. Eiden, Joshua Li, Martin MacKinnon, Joshua B. Garfinkel, Sarah Hooper, Yanling Liu, Mark T. Nelson, Alan P. Koretsky, Amreen Mughal

This study shows that electro-calcium uncoupling in endothelial cells precedes neurodegeneration and cognitive decline in 5xFAD mice.

bioRxiv · Jan 27, 2026 · PreprintNeuroscience

CodonTranslator: a conditional codon language model for codon optimization across all domains of life

Yanshuo Chen, Yuming Zhang, Joshua Li, Boxue Tian, Heng Huang

CodonTranslator is a Transformer-based model for codon optimization across species, achieving better codon usage and stability than existing methods.

bioRxiv · Nov 24, 2025 · PreprintBioinformatics

Neat1 alleviates ischemic injury in skeletal muscles

Kyungmin Kim, Tao Yu, Hyejin Mun, Dong Gun Oh, Sangyoon Lee, Mirae Kim, Jibeen Kim, Yuseon Kang, Joshua Li, Young Charles Jang, Je‐Hyun Yoon, Laura Hansen, Hyojung J. Choo

This study identifies Neat1 as a regulator of hypoxic response in aged skeletal muscle, showing that its overexpression protects against ischemic injury in a murine model.

bioRxiv · Nov 8, 2025 · PreprintCell Biology

NEST: Spatially-mapped cell-cell communication patterns using a deep learning-based attention mechanism

Fatema Tuz Zohora, Deisha Paliwal, Eugenia Flores Figueroa, Joshua Li, Tingxiao Gao, Faiyaz Notta, Gregory W. Schwartz

NEST detects cell-cell communication patterns using a deep learning-based attention mechanism, outperforming existing tools and identifying biologically relevant communication in various tissues and diseases.

Nature Methods · Jun 6, 2025Peer-reviewedBioinformatics