Author

Joshua R. Wydra

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Christopher Camitta· 1 shared Cynthia Zhi· 1 shared Daisy W. LeungiD· 1 shared David A. Price· 1 shared Jennifer M Alexander‐BrettiD· 1 shared Jessica A. Greven· 1 shared Jordyn D. Svoboda· 1 shared Mya Washington· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Christopher Camitta

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1 paper

Recent·Most cited

BiophysicsMolecular NeurodegenerationPeer-reviewedJan 9, 2025

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple AD ligands

Jessica A. Greven, Joshua R. Wydra, Rory A. Greer…·Tom J. Brett

This study maps TREM2-ligand interactions using biolayer interferometry, revealing shared binding surfaces for apoE4, oAb42, and TDP-43, and a unique site for IL-34.

40 citationstop 1%

humanproteomics

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