Author

Jessica A. Greven

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Jennifer M Alexander‐BrettiD· 2 shared Tom J. BrettiD· 2 shared Christopher Camitta· 1 shared Cynthia Zhi· 1 shared Daisy W. LeungiD· 1 shared David A. Price· 1 shared Jay C. NixiD· 1 shared Jordyn D. Svoboda· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersBiophysics

Jennifer M Alexander‐BrettORCID

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2 papers

Recent·Most cited

BiophysicsMolecular NeurodegenerationPeer-reviewedJan 9, 2025

Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple AD ligands

Jessica A. Greven, Joshua R. Wydra, Rory A. Greer…·Tom J. Brett

This study maps TREM2-ligand interactions using biolayer interferometry, revealing shared binding surfaces for apoE4, oAb42, and TDP-43, and a unique site for IL-34.

40 citationstop 1%

humanproteomics

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BiophysicsbioRxivPreprintMay 23, 2024

Structural and functional analysis of TREM2 interactions with amyloid beta reveal molecular mechanisms that mediate phagocytosis of oligomeric amyloid beta

Jessica A. Greven, Omar Osario, Jay C. Nix…·Tom J. Brett

5 citations

humanproteomics

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