Author

Judith A. Pate

Euan MacDonald Centre for Motor Neuron Disease Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jenna M. GregoryiD· 2 shared Judi O’ShaughnessyiD· 2 shared Olivia M. RifaiiD· 2 shared Barry W. McColliD· 1 shared Christopher R. SibleyiD· 1 shared Fergal M. WaldroniD· 1 shared James LongdeniD· 1 shared Karina McDadeiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Jenna M. GregoryORCID

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2 papers

Recent·Most cited

Random forest modelling of neuropathological features identifies microglial activation as an accurate pathological classifier of C9orf72-related amyotrophic lateral sclerosis

Olivia M. Rifai, James Longden, Judi O’Shaughnessy, Michael D.E. Sewell, Judith A. Pate, Karina McDade, Michael J. D. Daniels, Sharon Abrahams, Siddharthan Chandran, Barry W. McColl, Christopher R. Sibley, Jenna M. Gregory

The paper uses random forest modelling to identify microglial activation as a key classifier for C9orf72-related ALS and shows spatial FUS staining changes predict disease status.

The Journal of Pathology · Sep 7, 2022Peer-reviewedNeuroscience

pTDP-43 aggregates accumulate in the gut and other non-central nervous system tissues prior to symptom onset in amyotrophic lateral sclerosis

Samuel B. Pattle, Judi O’Shaughnessy, Olivia M. Rifai, Judith A. Pate, Mark Johan Arends, Fergal M. Waldron, Jenna M. Gregory

The paper identifies pTDP-43 aggregates in non-CNS tissues of ALS patients prior to symptom onset, suggesting systemic pathology beyond the central nervous system.

bioRxiv · Mar 17, 2022 · PreprintNeuroscience