Broad transcriptional dysregulation of brain and choroid plexus cell types with COVID-19
Andrew C. Yang, Fabian Kern, Patricia Morán Losada, Maayan R. Agam, Christina A. Maat, Georges Pierre Schmartz, Tobias Fehlmann, Julian A. Stein, Nicholas Schaum, Davis P. Lee, Kruti Calcuttawala, Ryan T. Vest, Daniela Berdnik, Nannan Lu, Oliver Hahn, , Tony Wyss‐Coray
The paper analyzes single-nucleus transcriptomes from brain and choroid plexus tissues of COVID-19 and influenza patients, identifying broad transcriptional dysregulation in multiple cell types and linking these changes to neurological symptoms.
Nature · Jun 21, 2021Peer-reviewedNeuroscience