Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging
James R. Occean, Na Yang, Yan Sun, Marshall S. Dawkins, Rachel B. Munk, Cédric Belair, Showkat Ahmad Dar, Carlos Anerillas, Lin Wang, Changyou Shi, Christopher Dunn, Michel Bernier, Nathan L. Price, Julie S. Kim, Chang‐Yi Cui, , Payel Sen
This study shows that DNA hydroxymethylation in gene bodies limits transcriptional changes with age in mouse and human tissues.
Nature Communications · Jul 28, 2024Peer-reviewedGenomics