Lin Wang

A Conserved Geometric Code: Extracellular Matrix Curvature Directs Cell Migration Strategy via Nuclear Mechanosensing

The paper shows ECM curvature directs cell migration through nuclear mechanosensing, revealing a geometric code influencing migration strategy and metastasis.

Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging

This study shows that DNA hydroxymethylation in gene bodies limits transcriptional changes with age in mouse and human tissues.

Diverse cell death signature based subtypes predict the prognosis and immune characteristics within glioma

This study identifies two DCD-related subtypes in glioma with distinct prognostic and immune characteristics using a risk score model based on DCD genes.

A hyper-quiescent chromatin state formed during aging is reversed by regeneration

The paper identifies an aging-associated chromatin state in mice and shows that liver regeneration reverses it.

Genomic insights into the population history and biological adaptation of Southwestern Chinese Hmong-Mien people

This study analyzes genome-wide SNPs from Hmong-Mien speakers to reveal genetic substructure, a new ancestral lineage, and adaptive signatures linked to nervous system functions.