Author

Junki Sho

RIKEN

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Organism:rat· 2 Organism:human· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Masayo TakahashiiD· 4 shared Michiko MandaiiD· 4 shared Akishi OnishiiD· 3 shared Aiko Ishimaru· 2 shared Chikako Morinaga· 2 shared Hung‐Ya TuiD· 2 shared Kazushi Yasuda· 2 shared Take MatsuyamaiD· 2 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersNeuroscience

Masayo TakahashiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mutation-agnostic gene insertion therapy for RHO-associated autosomal dominant retinitis pigmentosa using zinc finger nucleases

Akishi Onishi, Tetsushi Sakuma, Michiko Mandai, Takashi Watanabe, Takaho A. Endo, Wataru Nomura, Aiko Ishimaru, Kenichi Inoue, Junki Sho, Yoko Ohigashi, Yuki Nakano, Kazushi Yasuda, Atsuta Ozaki, Akiko Maeda, Chikako Morinaga, , Masayo Takahashi

This paper develops a mutation-agnostic gene insertion therapy for RHO-adRP using ZF-ND1-mediated HITI and validates its efficacy and safety in preclinical models.

bioRxiv · Jul 17, 2026 · PreprintGenetics

Efficient workflow for validating homology-independent targeted integration-mediated gene insertion in rod photoreceptor cells to treat dominant-negative mutations causing retinitis pigmentosa

Akishi Onishi, Yuji Tsunekawa, Michiko Mandai, Aiko Ishimaru, Yoko Ohigashi, Junki Sho, Kazushi Yasuda, Keiichiro Suzuki, Juan Carlos Izpisúa Belmonte, Fumio Matsuzaki, Masayo Takahashi

bioRxiv · Nov 8, 2023 · PreprintMolecular Biology

Self-organization, quality control, and preclinical studies of human iPSC-derived retinal sheets for tissue-transplantation therapy

Kenji Watari, Suguru Yamasaki, Hung‐Ya Tu, Masayuki Shikamura, Tatsuya Kamei, Hideki Adachi, Tomoaki Tochitani, Yasuyuki Kita, Aya Nakamura, Kazuki Ueyama, Keiichi Ono, Chikako Morinaga, Take Matsuyama, Junki Sho, Miyuki Nakamura, , Atsushi Kuwahara

The paper develops a quality control method and preclinical studies for human iPSC-derived retinal sheets for transplantation therapy, showing safety and functional integration in rat models.

Communications Biology · Feb 10, 2023Peer-reviewedNeuroscience

Genetically engineered retina for improved retinal reconstruction after transplantation

Take Matsuyama, Hung‐Ya Tu, Jianan Sun, Tomoyo Hashiguchi, Ryutaro Akiba, Junki Sho, Momo Fujii, Akishi Onishi, Masayo Takahashi, Michiko Mandai

This study shows genetically engineered retinal sheets improve visual recovery by enhancing neural integration and reducing aberrant activity after transplantation in mice.

iScience · Jul 16, 2021Peer-reviewedNeuroscience