Author

Atsuta Ozaki

Mie UniversityORCID 0000-0002-2359-5604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Michiko MandaiiD· 2 shared Aiko Ishimaru· 1 shared Akihiro Kawai· 1 shared Akiko Maeda· 1 shared Akishi OnishiiD· 1 shared Chikako Morinaga· 1 shared Du Peiyan· 1 shared Hiroshi KiyonariiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersGenetics

Michiko MandaiORCID

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2 papers

Recent·Most cited

Mutation-agnostic gene insertion therapy for RHO-associated autosomal dominant retinitis pigmentosa using zinc finger nucleases

Akishi Onishi, Tetsushi Sakuma, Michiko Mandai, Takashi Watanabe, Takaho A. Endo, Wataru Nomura, Aiko Ishimaru, Kenichi Inoue, Junki Sho, Yoko Ohigashi, Yuki Nakano, Kazushi Yasuda, Atsuta Ozaki, Akiko Maeda, Chikako Morinaga, , Masayo Takahashi

This paper develops a mutation-agnostic gene insertion therapy for RHO-adRP using ZF-ND1-mediated HITI and validates its efficacy and safety in preclinical models.

bioRxiv · Jul 17, 2026 · PreprintGenetics

Genome-edited retinal organoids restore host bipolar connectivity in the primate macula

Atsuta Ozaki, Akihiro Kawai, Ryutaro Akiba, Satoko Okayama, Nobuhiko Ohno, Keisuke Kajita, Tomohiro Masuda, Satoshi Yokota, Shinichiro ITO, Du Peiyan, Kenta Onoue, Shigenobu Yonemura, Mineo Kondo, Yasuo Kurimoto, Yingbin Fu, Michiko Mandai

This study transplants genome-edited retinal organoids into a primate macular degeneration model, showing host bipolar cells rewire and form functional synapses with grafted photoreceptors.

bioRxiv · Aug 21, 2025 · PreprintNeuroscience