Migraine inhibitor olcegepant reduces weight loss and IL-6 release in SARS-CoV-2 infected older mice with neurological signs
Shafaqat M. Rahman, David W. Buchholz, Brian Imbiakha, Mason C. Jager, Justin Leach, Raven M. Osborn, Ann O. Birmingham, Stephen Dewhurst, Hector C. Aguilar, Anne E. Luebke
This study shows that olcegepant reduces weight loss and IL-6 release in older mice infected with SARS-CoV-2, suggesting potential neuroprotective effects against coronavirus-induced inflammation.
Journal of Virology · May 30, 2024Peer-reviewedNeuroscience