Author

K. A. Murgas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Weistuch· 2 shared J. O. Deasy· 2 shared A. G. Mikos· 1 shared A. Hall· 1 shared A. R. Tannenbaum· 1 shared A. Tannenbaum· 1 shared B. L. King· 1 shared C. C. Maley· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCancer Biology

C. Weistuch

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Author profile →

3 papers

Recent·Most cited

Growth Dynamics of Ductal Carcinoma in Situ Recapitulate Normal Breast Development

M. D. Ryser, M. A. Greenwald, I. C. Sorribes, L. M. King, A. Hall, J. Geradts, D. L. Weaver, D. Mallo, S. Holloway, D. Monyak, G. Gumbert, S. Vaez-Ghaemi, E. Wu, K. A. Murgas, L. J. Grimm, , S. Hwang

This study reconstructs DCIS growth dynamics using somatic mutation topography, revealing a multiclonal, branching morphogenesis-like pattern consistent with a new Comet model of tumorigenesis.

bioRxiv · Oct 1, 2023 · PreprintCancer Biology

Mapping the Single-cell Differentiation Landscape of Osteosarcoma

D. D. Truong, C. Weistuch, K. A. Murgas, P. Admane, B. L. King, J. Chauviere Lee, S.-E. Lamhamedi-Cherradi, J. Swaminathan, N. C. Daw, N. Gordon, V. Gopalakrishnan, R. G. Gorlick, N. Somaiah, J. O. Deasy, A. G. Mikos, , J. Ludwig

The paper maps the differentiation landscape of osteosarcoma using single-cell data to identify gene modules linked to cell fate and patient survival.

bioRxiv · Sep 13, 2023Cancer Biology

Functional transcriptional signatures for tumor-type-agnostic phenotype prediction

C. Weistuch, K. A. Murgas, J. Zhu, L. Norton, K. A. Dill, A. R. Tannenbaum, J. O. Deasy

The paper identifies six transcriptomic archetypes from normal tissues that correlate with cancer patient survival and drug sensitivity, suggesting cancer adopts normal tissue transcriptional features.

bioRxiv · Apr 12, 2023 · PreprintCancer Biology