Author

J. Swaminathan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

B. M. Floyd· 2 shared D. D. Truong· 2 shared E. M. Marcotte· 2 shared E. V. Anslyn· 2 shared N. C. Daw· 2 shared N. Gordon· 2 shared S.-E. Lamhamedi-Cherradi· 2 shared V. Gopalakrishnan· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

B. M. Floyd

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Mapping the Single-cell Differentiation Landscape of Osteosarcoma

D. D. Truong, C. Weistuch, K. A. Murgas, P. Admane, B. L. King, J. Chauviere Lee, S.-E. Lamhamedi-Cherradi, J. Swaminathan, N. C. Daw, N. Gordon, V. Gopalakrishnan, R. G. Gorlick, N. Somaiah, J. O. Deasy, A. G. Mikos, , J. Ludwig

The paper maps the differentiation landscape of osteosarcoma using single-cell data to identify gene modules linked to cell fate and patient survival.

bioRxiv · Sep 13, 2023Cancer Biology

Design and Evaluation of an Affordable Hypoxic Chamber with Comprehensive Environmental Control for Research Applications

S. A. Roshan, J. Swaminathan, M. Kandasamy, A. Muthuswamy

The paper designs and evaluates an affordable hypoxic chamber with environmental control for research, capable of regulating oxygen, CO2, and humidity levels.

bioRxiv · Jun 21, 2023 · PreprintBioengineering

Dissociation protocols used for sarcoma tissues bias the transcriptome observed in single-cell and single-nucleus RNA sequencing

D. D. Truong, S.-E. Lamhamedi-Cherradi, R. W. Porter, S. Krishnan, J. Swaminathan, A. Gibson, A. J. Lazar, J. A. Livingston, V. Gopalakrishnan, N. Gordon, N. C. Daw, R. Gorlick, J. A. Ludwig

The paper shows that dissociation methods bias transcriptomes in sarcoma single-cell and single-nucleus RNA-seq, and demonstrates computational correction of these biases.

bioRxiv · Jan 21, 2022 · PreprintCancer Biology

Photoredox-catalyzed decarboxylative C-terminal differentiation for bulk and single molecule proteomics

L. Zhang, B. M. Floyd, M. Chilamari, J. Mapes, J. Swaminathan, S. Bloom, E. M. Marcotte, E. V. Anslyn

This paper introduces a photoredox-catalyzed method for C-terminal labeling of peptides, applicable to bulk and single-molecule proteomics, achieving over 50% labeling efficiency across proteomes.

bioRxiv · Jul 8, 2021Biochemistry

Solid-Phase Peptide Capture and Release for Bulk and Single-Molecule Proteomics

C. J. Howard, B. M. Floyd, A. M. Bardo, J. Swaminathan, E. M. Marcotte, E. V. Anslyn

This paper introduces a solid-phase peptide capture method for bulk and single-molecule proteomics, demonstrating its effectiveness in isolating and modifying peptides from cell lysates.

bioRxiv · Jan 13, 2020Biochemistry