Author

K. Aguirre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

E. Piskounova· 2 shared A. S. Doane· 1 shared A. Verma· 1 shared A. Wang· 1 shared B. E. Howitt· 1 shared B. Liang· 1 shared C. Y. Yeh· 1 shared D. Q. Licona· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

E. Piskounova

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mapping ovarian cancer spatial organization uncovers immune evasion drivers at the genetic, cellular, and tissue level

C. Y. Yeh, K. Aguirre, O. Laveroni, S. Kim, A. Wang, B. Liang, X. Zhang, L. M. Han, R. Valbuena, S. K. Plevritis, M. C. Bassik, M. P. Snyder, B. E. Howitt, L. Jerby

This study maps ovarian cancer spatial organization and identifies immune evasion drivers through single-cell spatial transcriptomics and CRISPR screens.

bioRxiv · Oct 16, 2023Cancer Biology

Transcriptional Isoforms of NAD+ Kinase regulate oxidative stress resistance and melanoma metastasis

G. Cascio, K. Aguirre, K. Church, R. O. Hughes, L. Nease, D. Q. Licona, I. Delclaux, M. Zerhouni, E. Piskounova

The paper identifies NADK isoform 3 as a key regulator of oxidative stress resistance and metastasis in melanoma by enhancing NADP(H) pools.

bioRxiv · Feb 2, 2023Cancer Biology

A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

M. M. Drozdz, A. S. Doane, R. Alkallas, G. Desman, R. Bareja, M. Reilly, J. Bang, M. Yusupova, J. You, J. Z. Wang, A. Verma, K. Aguirre, E. Kane, I. R. Watson, O. Elemento, , J. H. Zippin

The paper identifies a nuclear cAMP microdomain that suppresses tumor growth by inhibiting YAP in the Hippo pathway.

bioRxiv · Nov 15, 2021Cancer Biology