M. Reilly

Hypoxic volatile metabolic markers in the MDA-MB-231 breast cancer cell line

This study identifies four volatile organic compounds altered in MDA-MB-231 breast cancer cells under hypoxia using gas chromatography mass spectrometry.

A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation

The paper identifies a nuclear cAMP microdomain that suppresses tumor growth by inhibiting YAP in the Hippo pathway.

Bisphenol S and bisphenol F are less disruptive to cardiac electrophysiology and potentially safer for use in medical products, as compared to bisphenol A

This study compares the effects of bisphenol analogues on cardiac electrophysiology, finding BPA and BPF inhibit ion channels more than BPS.

Brazilin Removes Toxic alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium

This paper shows Brazilin inhibits alpha-synuclein fibril formation and reduces toxicity in Parkinson's disease by altering conformational equilibrium.

Chronic Perinatal Hypoxia Delays Cardiac Maturation in a Mouse Model for Cyanotic Congenital Heart Disease

This study examines the effects of chronic perinatal hypoxia on cardiac development in a mouse model of cyanotic congenital heart disease, finding persistent electrophysiological and functional impairments.

Potential consequences of the red blood cell storage lesion on cardiac electrophysiology

This study shows that older red blood cell units affect cardiac electrophysiology, likely due to biochemical changes, including hyperkalemia, and highlights risks for certain patient groups.

Age-dependent changes in electrophysiology and calcium handling: implications for pediatric cardiac research

This study examines age-related changes in cardiac electrophysiology and calcium handling in rats, finding slowed conduction, prolonged action potentials, and altered gene expression in immature hearts.