Author

D. S. Williams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Buchert· 2 shared M. Ernst· 2 shared M. F. Eissmann· 2 shared A. Bousssioutas· 1 shared A. Dhingra· 1 shared A. H. Allam· 1 shared A. Huber· 1 shared A. R. Poh· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCancer Biology

M. Buchert

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within Interleukin-6 family cytokines

A. Huber, A. H. Allam, C. Dijkstra, S. Thiem, J. Huynh, A. R. Poh, J. Konecnik, S. P. Jacob, R. Busuttil, Y. Liao, D. Chasinga, W. Shi, M. G. Alorro, S. Forrow, D. V. F. Tauriello, , M. F. Eissmann

This study identifies IL6/STAT3 signaling as a therapeutic target for TP53-mutant gastric cancer by showing its role in metastatic progression driven by mutant Trp53.

bioRxiv · Apr 22, 2024Cancer Biology

EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis

C. M. Reehorst, R. Nightingale, I. Y. Luk, L. Jenkins, F. Koentgen, D. S. Williams, C. Darido, F. Tan, H. Anderton, M. Chopin, K. Schoffer, M. F. Eissmann, M. Buchert, D. Mouradov, O. M. Sieber, , J. M. Mariadason

This study shows that EHF is essential for epidermal and colonic epithelial homeostasis and acts as a tumor suppressor in colorectal cancer.

bioRxiv · Mar 1, 2021Cell Biology

Peroxisome turnover and diurnal modulation of antioxidant activity in retinal pigment epithelia utilizes microtubule-associated protein 1 light chain 3B

L. L. Daniele, J. Caughey, S. Volland, R. C. Sharp, A. Dhingra, D. S. Williams, N. J. Philp, K. Boesze-Battaglia

The paper investigates peroxisome activity and turnover in RPE cells, finding that catalase activity peaks in the morning and is regulated by LC3B, which affects autophagic organelle turnover.

bioRxiv · Jul 1, 2019Biochemistry

Myosin II isoforms play distinct roles in adherens junction biogenesis

B. Ladoux, R.-M. Mege, T. Dang, M. Heuze, J. Van Hest, G. Sankara, P. Marcq, J. D'Alessandro, V. Cellerin, D. S. Williams

This study identifies distinct roles of myosin II isoforms in adherens junction biogenesis, showing NMIIA provides mechanical force for junction maintenance while NMIIB facilitates E-cadherin clustering and anisotropic stress.

bioRxiv · Mar 16, 2019Cell Biology