A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines
S. Ajay Castro, I. J. Passmore, D. Ndeh, H. A. Shaw, A. Ruda, K. Burns, S. Thomson, R. Nagar, K. Alagesan, K. Lucas, S. Abouelhadid, M. Reglinski, U. Schwarz- Linek, F. Mawas, G. Widmalm, , H. C. Dorfmueller
This study develops a platform for recombinant production of Group A Streptococcus glycoconjugate vaccines using E. coli, confirming their structural integrity and immunogenicity in animal models.
bioRxiv · Mar 1, 2024Microbiology