Author

K. C. Keim

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. R. Horswill· 2 shared A. B. Herr· 1 shared C. J. Langouët-Astrie· 1 shared C. Wang· 1 shared D. A. Robinson· 1 shared E. P. Schmidt· 1 shared H. Crosby· 1 shared J. A. Crawford· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

A. R. Horswill

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2 papers

Recent·Most cited

Staphylococcus aureus skin colonization is mediated by SasG lectin variation

K. B. Mills, J. J. Maciag, C. Wang, J. A. Crawford, T. J. Enroth, K. C. Keim, Y. F. Dufrene, D. A. Robinson, P. D. Fey, A. B. Herr, A. R. Horswill

This study identifies SasG-II, a variant of the S. aureus surface protein, which binds to a broader range of ligands, enhancing its ability to colonize skin.

bioRxiv · Nov 20, 2023 · PreprintMicrobiology

Host-derived protease promotes aggregation of Staphylococcus aureus by cleaving the surface protein SasG

H. Crosby, K. C. Keim, J. Kwiecinski, C. J. Langouët-Astrie, K. Oshima, W. B. LaRiviere, E. P. Schmidt, A. R. Horswill

This study shows that host-derived protease cleaves SasG, promoting S. aureus aggregation and virulence in mouse infections.

bioRxiv · Dec 13, 2022 · PreprintMicrobiology