Author

K. C. Patra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. D'Alessandro· 1 shared A. Martines· 1 shared B. Shamsaei· 1 shared B. Vemuri· 1 shared C. Bartolacci· 1 shared D. L. Swaney· 1 shared D. R. Plas· 1 shared D. Secic· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. D'Alessandro

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2 papers

Recent·Most cited

Copper drives remodeling of metabolic state and progression of clear cell renal cell carcinoma

M. Czyzyk-Krzeska, M. E. Bischoff, B. Shamsaei, J. Yang, D. Secic, B. Vemuri, J. A. Reisz, A. D'Alessandro, C. Bartolacci, R. Adamczyk, L. Schmidt, J. Wang, A. Martines, J. Biesiada, K. E. Vest, , J. T. Cunningham

This study shows copper drives metabolic remodeling and progression in clear cell renal cell carcinoma by coordinating bioenergy, biosynthesis, and redox homeostasis.

bioRxiv · Jan 16, 2024Cancer Biology

Oncogenic PKA signaling stabilizes MYC oncoproteins via an aurora kinase A-dependent mechanism

G. K. L. Chan, S. Maisel, Y. C. Hwang, R. R. B. Wolber, P. Vu, K. C. Patra, M. Bouhaddou, H. L. Kenerson, R. S. Yeung, D. L. Swaney, N. J. Krogan, R. E. Turnham, J. D. Scott, K. J. Riehle, N. Bardeesy, J. D. Gordan

This study identifies two PKA-driven oncogenic mechanisms, showing AURKA stabilizes MYC oncoproteins through a PIM2-mediated feedback loop, and suggests CD-532 as a potential therapeutic target.

bioRxiv · Apr 16, 2021Cancer Biology