Author

K. C. Sproll

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

B. Miles· 2 shared J. A. Aguirre-Ghiso· 2 shared A. R. Nobre· 1 shared A. Rodriguez Martinez· 1 shared B. D. Khalil· 1 shared B. Khalil· 1 shared C. A. Rodriguez-Tirado· 1 shared D. Filipescu· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. Miles

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

MacroH2A impedes metastatic growth by enforcing a discrete dormancy program in disseminated cancer cells

D. Sun, D. Filipescu, D. Hasson, D. K. Singh, S. Carcamo, B. Khalil, B. Miles, W. Westra, K. C. Sproll, E. Bernstein, J. A. Aguirre-Ghiso

This study shows macroH2A2 promotes dormancy in disseminated cancer cells, preventing metastasis without requiring known dormancy factors.

bioRxiv · Dec 7, 2021Cancer Biology

A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy

B. D. Khalil, R. Sanchez, T. Rahman, C. A. Rodriguez-Tirado, S. Moritsch, A. Rodriguez Martinez, B. Miles, E. Farias, M. Mezei, J. F. Cheung, A. R. Nobre, N. Kale, K. C. Sproll, M. S. Sosa, J. A. Aguirre-Ghiso

This study identifies a novel NR2F1 agonist, C26, that suppresses metastasis by inducing cancer cell dormancy through NR2F1 activation in HNSCC.

bioRxiv · Jan 30, 2021Cancer Biology