Author

M. Mezei

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. C. Stone· 1 shared A. R. Nobre· 1 shared A. Rodriguez Martinez· 1 shared A. Schlessinger· 1 shared B. D. Khalil· 1 shared B. Miles· 1 shared B. Zhang· 1 shared C. A. Rodriguez-Tirado· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

A. C. Stone

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Computational model of the full-length TSH receptor

M. Mezei, R. Latif, T. F. Davies

The paper models the full-length TSH receptor using AI and molecular dynamics, revealing the linker region's flexibility and its interaction with TSH ligand.

bioRxiv · Jul 13, 2022Biophysics

Substrate Binding and Inhibition of the Anion Exchanger 1 Transporter

M. J. Capper, S. Yang, A. C. Stone, S. Vatansever, G. Zilberg, Y. K. Mathiharan, R. Habib, K. Hutchinson, A. Schlessinger, M. Mezei, R. Osman, B. Zhang, D. Wacker

The paper presents high-resolution cryo-EM structures of the full-length human AE1 transporter in various states, revealing substrate binding, inhibition mechanisms, and lipid/sterol binding sites.

bioRxiv · Feb 11, 2022Biochemistry

A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy

B. D. Khalil, R. Sanchez, T. Rahman, C. A. Rodriguez-Tirado, S. Moritsch, A. Rodriguez Martinez, B. Miles, E. Farias, M. Mezei, J. F. Cheung, A. R. Nobre, N. Kale, K. C. Sproll, M. S. Sosa, J. A. Aguirre-Ghiso

This study identifies a novel NR2F1 agonist, C26, that suppresses metastasis by inducing cancer cell dormancy through NR2F1 activation in HNSCC.

bioRxiv · Jan 30, 2021Cancer Biology