Author

A. R. Nobre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 4

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

J. A. Aguirre-Ghiso· 4 shared D. K. Singh· 2 shared E. Farias· 2 shared J. F. Cheung· 2 shared M. S. Sosa· 2 shared N. Kale· 2 shared A. Birbrair· 1 shared A. C. Rigby· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCancer Biology

J. A. Aguirre-Ghiso

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4 papers

Recent·Most cited

Epigenetic reprogramming of DCCs into dormancy suppresses metastasis via restored TGFβ-SMAD4 signaling.

D. K. Singh, E. Farias, S. Carcamo, D. Hasson, D. Sun, J. Cheung, A. R. Nobre, N. Kale, M. S. Sosa, E. Bernstein, J. A. Aguirre-Ghiso

The paper shows that AZA+atRA treatment induces dormancy in DCCs by restoring TGFβ-SMAD4 signaling, suppressing lung metastasis.

bioRxiv · Aug 1, 2021Cancer Biology

PERK inhibition blocks metastasis initiation by limiting UPR-dependent survival of dormant disseminated cancer cells

V. Calvo, W. Zheng, K. A. Staschke, A. R. Nobre, E. F. Farias, A. Nowacek, M. Mulvihill, A. C. Rigby, J. A. Aguirre-Ghiso

This study shows that PERK inhibition reduces metastasis by targeting dormant cancer cells through UPR-dependent mechanisms.

bioRxiv · Jul 30, 2021Cancer Biology

A specific agonist of the orphan nuclear receptor NR2F1 suppresses metastasis through the induction of cancer cell dormancy

B. D. Khalil, R. Sanchez, T. Rahman, C. A. Rodriguez-Tirado, S. Moritsch, A. Rodriguez Martinez, B. Miles, E. Farias, M. Mezei, J. F. Cheung, A. R. Nobre, N. Kale, K. C. Sproll, M. S. Sosa, J. A. Aguirre-Ghiso

This study identifies a novel NR2F1 agonist, C26, that suppresses metastasis by inducing cancer cell dormancy through NR2F1 activation in HNSCC.

bioRxiv · Jan 30, 2021Cancer Biology

NG2+/Nestin+ mesenchymal stem cells dictate DTC dormancy in the bone marrow through TGFβ2

A. R. Nobre, E. Risson, D. K. Singh, J. S. Di Martino, J. F. Cheung, J. Wang, J. Johnson, H. G. Russnes, J. J. Bravo-Cordero, A. Birbrair, B. Naume, M. Azhar, P. S. Frenette, J. A. Aguirre-Ghiso

This study shows NG2+/Nestin+ mesenchymal stem cells in the bone marrow use TGFβ2 to induce dormancy in breast cancer disseminated tumor cells.

bioRxiv · Oct 22, 2020Cancer Biology