Author

K. Florczak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

F. Barrow· 3 shared G. Fredrickson· 3 shared H. Wang· 3 shared X. Revelo· 3 shared P. Parthiban· 2 shared S. Ikramuddin· 2 shared A. Bartolomucci· 1 shared A. Herman· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersPhysiology

F. Barrow

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pyruvate Oxidation Sustains B Cell Antigen-Specific Activation to Exacerbate MASH

F. Barrow, H. Wang, G. Fredrickson, K. Florczak, E. Ciske, S. Khanal, P. Parthiban, H. Nguyen, E. Rios, E. Kostallari, X. Revelo

This study shows that B cell pyruvate oxidation supports antigen-specific activation, driving inflammation and fibrosis in MASH.

bioRxiv · Nov 13, 2023 · PreprintPhysiology

Hepatic lipid-associated macrophages mediate the beneficial effects of bariatric surgery against MASH

G. Fredrickson, K. Florczak, F. Barrow, K. Dietsche, H. Wang, P. Parthiban, R. Almutlaq, O. Adeyi, A. Herman, A. Bartolomucci, C. Staley, C. Jahansouz, J. W. Williams, D. Mashek, S. Ikramuddin, X. Revelo

This study shows that bariatric surgery reduces MASH through TREM2-expressing hepatic macrophages, independent of weight loss.

bioRxiv · Jun 11, 2023 · PreprintPhysiology

Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH

H. Wang, F. Barrow, G. Fredrickson, K. Florczak, S. Ikramuddin, H.-B. Ruan, S. C. Jameson, X. Revelo

This study identifies dysfunctional T follicular helper cells in NASH as a driver of intestinal and hepatic inflammation using a mouse model.

bioRxiv · Jun 7, 2023 · PreprintImmunology