Author

S. C. Jameson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:cell type annotation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

H. Borges da Silva· 3 shared C. Peng· 2 shared H. Wang· 2 shared K. M. Wanhainen· 2 shared S. van Dijk· 2 shared T. Vardam-Kaur· 2 shared A. A. Hurwitz· 1 shared A. Banuelos· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersImmunology

H. Borges da Silva

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH

H. Wang, F. Barrow, G. Fredrickson, K. Florczak, S. Ikramuddin, H.-B. Ruan, S. C. Jameson, X. Revelo

This study identifies dysfunctional T follicular helper cells in NASH as a driver of intestinal and hepatic inflammation using a mouse model.

bioRxiv · Jun 7, 2023 · PreprintImmunology

The ATP-exporting channel Pannexin-1 promotes CD8+ T cell effector and memory responses

T. Vardam-Kaur, A. Banuelos, M. Gabaldon-Parish, B. G. Macedo, C. L. Salgado, K. M. Wanhainen, M. H. Zhou, S. van Dijk, I. Santiago-Carvalho, A. S. Beniwal, C. L. Leff, C. Peng, N. L. Tran, S. C. Jameson, H. Borges da Silva

This study shows that Pannexin-1 promotes CD8+ T cell effector and memory responses through distinct mechanisms involving eATP export and purinergic receptor activation.

bioRxiv · Apr 19, 2023Immunology

The extracellular ATP receptor P2RX7 imprints a pro-memory transcriptional signature in effector CD8+ T cells

T. Vardam-Kaur, S. van Dijk, C. Peng, K. M. Wanhainen, S. C. Jameson, H. Borges da Silva

This study shows that P2RX7 expression in effector CD8+ T cells influences their differentiation into central and resident memory cells through transcriptional changes.

bioRxiv · May 25, 2021 · PreprintImmunology

γδ-Thymocyte Maturation and Emigration

K. Joannou, D. P. Golec, H. Wang, L. M. Henao-Caviedes, J. F. May, R. G. Kelly, R. Chan, S. C. Jameson, T. A. Baldwin

This study shows that adult mice have two distinct streams of γδ-T cells: one maturing in the periphery and another completing maturation in the thymus, with a fetal-derived resident population.

bioRxiv · Mar 19, 2021 · PreprintImmunology

Non-deletional CD8+ T cell self-tolerance permits responsiveness but limits tissue damage

E. N. Truckenbrod, K. S. Burrack, T. P. Knutson, H. Borges da Silva, K. E. Block, K. R. Stagliano, A. A. Hurwitz, R. B. Fulton, K. Renkema, S. C. Jameson

The paper shows that self-tolerant CD8+ T cells can respond but limit tissue damage, with functional tolerance linked to reduced CD25 expression and gene expression profiles.

bioRxiv · Dec 16, 2020Immunology