Author

K. Grunewald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:host-pathogen & immune response· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

C. Busch· 2 shared D. Vogel· 2 shared H. M. Williams· 2 shared M. Milewski· 2 shared M. Rosenthal· 2 shared S. Cusack· 2 shared S. R. Thorkelsson· 2 shared B. Maertens· 1 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersBiochemistry

C. Busch

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum

V. Prazak, D. Vasishtan, K. Grunewald, R. G. Douglas, J. L. Ferreira

This study visualizes F-actin in Plasmodium falciparum using electron cryo-tomography, revealing its structure and dynamics during gliding and its presence in the nucleus.

bioRxiv · Apr 22, 2024 · PreprintMicrobiology

Structural snapshots of phenuivirus cap-snatching and transcription

H. M. Williams, S. R. Thorkelsson, D. Vogel, C. Busch, M. Milewski, S. Cusack, K. Grunewald, E. R. J. Quemin, M. Rosenthal

The paper presents cryo-EM structures of SFTSV L protein during cap-snatching and transcription, revealing conformational changes and RNA binding mechanisms.

bioRxiv · Nov 29, 2023Biochemistry

Modeling flexible protein structure with AlphaFold2 and cross-linking mass spectrometry

K. Manalastas-Cantos, K. R. Adoni, M. Pfeifer, B. Maertens, K. Grunewald, K. Thalassinos, M. Topf

The paper introduces a pipeline combining AlphaFold2 and XL-MS to model protein conformations, showing improved accuracy in identifying correct structures using new scores.

bioRxiv · Sep 11, 2023Biochemistry

Structural insights into viral genome replication by the Severe fever with thrombocytopenia syndrome virus L protein

H. M. Williams, S. R. Thorkelsson, D. Vogel, M. Milewski, C. Busch, S. Cusack, K. Grunewald, E. Quemin, M. Rosenthal

This study presents cryo-EM structures of the SFTSV L protein during genome replication, revealing RNA binding and elongation mechanisms.

Nucleic Acids Research · Jan 18, 2023Peer-reviewedBiochemistry