ImmunologybioRxiv
Viperin binds STING and enhances the type-I interferon response following dsDNA detection
K. M. Crosse, E. A. Monson, A. B. Dumbrepatil…·K. J. Helbig
This study identifies Viperin's role in enhancing the type-I interferon response by binding STING and promoting TBK1 ubiquitination, thereby strengthening antiviral immunity against dsDNA.
DOI 10.1111/imcb.12420