Author

K. Höfer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:E. coli· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Wolfram-Schauerte· 3 shared N. Pozhydaieva· 3 shared A. A. R. Rojas· 2 shared D. Schindler· 2 shared F. A. Billau· 2 shared N. Paczia· 2 shared A. Jäschke· 1 shared A. Moskalchuk· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

M. Wolfram-Schauerte

Mutual co-authors in cluster

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3 papers

Recent·Most cited

T4 phage RNA is NAD-capped and alters the NAD-cap epitranscriptome of Escherichia coli during infection

M. Wolfram-Schauerte, H. Keuthen, A. Moskalchuk, T. Ueffing, N. Pozhydaieva, A. A. R. Rojas, D. Schindler, S. Kaiser, N. Paczia, K. Höfer

This study identifies NAD-capped RNAs during T4 phage infection of E. coli, showing dynamic changes in NAD-capping and revealing a phage-encoded Nudix hydrolase involved in NAD-RNA decapping.

bioRxiv · Apr 4, 2024 · PreprintMicrobiology

Temporal epigenome modulation enables efficient bacteriophage engineering and functional analysis of phage DNA modifications

N. Pozhydaieva, F. A. Billau, M. Wolfram-Schauerte, A. A. R. Rojas, N. Paczia, D. Schindler, K. Höfer

The paper describes a method to temporarily modulate phage DNA modifications using NgTET, enabling efficient Cas-mediated mutagenesis and functional analysis of phage epigenome.

bioRxiv · Jan 28, 2024Microbiology

A viral ADP-ribosyltransferase attaches RNA chains to host proteins

M. Wolfram-Schauerte, N. Pozhydaieva, J. Grawenhoff, L. M. Welp, I. Silbern, A. Wulf, F. A. Billau, T. Glatter, H. Urlaub, A. Jäschke, K. Höfer

This study identifies a viral ADP-ribosyltransferase, ModB, that attaches RNA chains to host proteins through an 'RNAylation' reaction, revealing a novel role for NAD-RNA in modulating host translation.

bioRxiv · Jun 4, 2021Microbiology