Multivariate chemogenomic screening prioritizes new macrofilaricidal leads
N. J. Wheeler, K. T. Ryan, K. J. Gallo, C. R. Henthorn, S. S. Ericksen, J. D. Chan, M. Zamanian
This study uses a multivariate screen to identify macrofilaricidal compounds, finding 17 compounds with strong effects on adult filariae and five with high potency against adults but low potency against microfilariae.
bioRxiv · Jul 25, 2022 · PreprintMicrobiology