Author

C. R. Henthorn

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

M. Zamanian· 2 shared E. K. Neumann· 1 shared J. D. Chan· 1 shared K. J. Gallo· 1 shared K. T. Ryan· 1 shared N. J. Wheeler· 1 shared P. M. Airs· 1 shared S. S. Ericksen· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

M. Zamanian

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Author profile →

2 papers

Recent·Most cited

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolution.

C. R. Henthorn, P. M. Airs, E. K. Neumann, M. Zamanian

This study uses single-cell analysis to identify the cellular origins of secretory products and anthelmintic responses in Brugia malayi microfilariae, revealing cell-specific expression patterns and introducing a cell culture model.

bioRxiv · Aug 30, 2022Microbiology

Multivariate chemogenomic screening prioritizes new macrofilaricidal leads

N. J. Wheeler, K. T. Ryan, K. J. Gallo, C. R. Henthorn, S. S. Ericksen, J. D. Chan, M. Zamanian

This study uses a multivariate screen to identify macrofilaricidal compounds, finding 17 compounds with strong effects on adult filariae and five with high potency against adults but low potency against microfilariae.

bioRxiv · Jul 25, 2022 · PreprintMicrobiology