Author

K. J. Green

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 6 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell signaling & trafficking· 5 Research Focus:cell type annotation· 5 Organism:human· 5 Assay:proteomics· 5 Organism:mouse· 4 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2

Frequent Co-Authors

J. L. Koetsier· 7 shared J. A. Broussard· 4 shared H. E. Burks· 3 shared J. L. Johnson· 3 shared M. Hegazy· 3 shared Q. R. Roth-Carter· 3 shared A. L. Huffine· 2 shared C. R. Arnette· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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7 shared papersCell Biology

J. L. Koetsier

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Author profile →

8 papers

Recent·Most cited

Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasis

B. N. Nanavati, I. Noordstra, S. Verma, K. Duszyc, K. J. Green, A. S. Yap

The paper identifies a mechanism where desmosome-anchored intermediate filaments enable RhoA signaling at adherens junctions to maintain epithelial homeostasis under tension.

bioRxiv · Feb 23, 2023 · PreprintCell Biology

Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAFV600E-induced cellular senescence in human melanocytes

X. Tong, H. E. Burks, Z. Ren, J. L. Koetsier, Q. R. Roth-Carter, K. J. Green

The paper shows that loss of desmoglein 1 in keratinocytes reduces senescence in BRAFV600E-expressing melanocytes by promoting NTN4 expression.

bioRxiv · Feb 16, 2023Cell Biology

Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

H. E. Burks, J. L. Pokorny, J. L. Koetsier, Q. R. Roth-Carter, C. R. Arnette, P. Gerami, J. T. Seykora, J. L. Johnson, K. J. Green

The paper shows melanoma cells exploit keratinocyte Dsg1 reduction via paracrine signaling to enhance tumor spread through CXCL1/CXCR2 and Snai2/Grhl1 pathways.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology

PP2A-B55α controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus

A. L. Perl, J. L. Koetsier, K. J. Green

The paper identifies PP2A-B55α as a phosphatase regulating desmoplakin phosphorylation and intercellular adhesion in keratinocytes.

bioRxiv · Oct 19, 2022 · PreprintCell Biology

Epidermal Stratification Requires Retromer-Mediated Desmoglein-1 Recycling

M. Hegazy, J. L. Koetsier, A. L. Huffine, J. A. Broussard, B. M. Godsel, L. M. Godsel, K. J. Green

This study identifies retromer-mediated recycling of Desmoglein-1 as essential for epidermal stratification and differentiation.

bioRxiv · Oct 25, 2021Cell Biology

Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

L. M. Godsel, Q. R. Roth-Carter, J. L. Koetsier, L. C. Tsoi, J. A. Broussard, G. N. Fitz, S. M. Lloyd, J. Kweon, A. L. Huffine, H. E. Burks, M. Hegazy, S. Amagai, P. W. Harms, J. L. Johnson, G. Urciuoli, , K. J. Green

This study investigates the systemic inflammatory response in Dsg1-deficient mice and humans, revealing a psoriatic-like IL-17-skewed inflammation due to genetic Dsg1 loss.

bioRxiv · Dec 1, 2020 · PreprintImmunology

Desmosomes polarize mechanical signaling to govern epidermal tissue form and function

J. A. Broussard, J. L. Koetsier, M. Hegazy, K. J. Green

This study shows desmosomes and intermediate filaments regulate mechanical polarization in epidermis, influencing layer-specific functions and barrier formation.

bioRxiv · Jan 21, 2020 · PreprintCell Biology

Keratinocyte desmoglein 1 regulates the epidermal microenvironment and tanning response

C. R. Arnette, J. L. Koetsier, J. A. Broussard, P. Gerami, J. L. Johnson, K. J. Green

This study shows that Dsg1 in keratinocytes regulates melanocyte communication and tanning by affecting cytokine secretion and melanin production.

bioRxiv · Sep 20, 2018Cell Biology