Author

J. T. Seykora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Anderson· 2 shared B. C. Capell· 2 shared C. A. Natale· 2 shared J. Zou· 2 shared K. Ge· 2 shared T. W. Ridky· 2 shared A. Trautz· 1 shared C. Aguirre-Portoles· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Anderson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Analysis of human GPER expression in normal tissues and select cancers using immunohistochemistry

C. A. Natale, J. T. Seykora, T. W. Ridky

This study uses immunohistochemistry with a new antibody to show GPER expression varies across normal and cancer tissues.

bioRxiv · Mar 9, 2023 · PreprintPathology

Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

H. E. Burks, J. L. Pokorny, J. L. Koetsier, Q. R. Roth-Carter, C. R. Arnette, P. Gerami, J. T. Seykora, J. L. Johnson, K. J. Green

The paper shows melanoma cells exploit keratinocyte Dsg1 reduction via paracrine signaling to enhance tumor spread through CXCL1/CXCR2 and Snai2/Grhl1 pathways.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology

H3K36M provokes cellular plasticity to drive aberrant glandular formation and squamous carcinogenesis

E. K. Ko, A. Anderson, J. Zou, S. Huang, S. Cho, F. Alawi, S. Prouty, V. Lee, K. Ge, J. T. Seykora, B. C. Capell

This study shows that H3K36M oncohistone disrupts epithelial differentiation, increases cellular plasticity, and drives squamous carcinogenesis by altering histone modifications.

bioRxiv · Aug 19, 2022 · PreprintCancer Biology

MLL4 is a critical mediator of differentiation and ferroptosis in the epidermis

S. Egolf, J. Zou, A. Anderson, Y. Aubert, K. Ge, J. T. Seykora, B. C. Capell

This study identifies MLL4's role in promoting epidermal differentiation and ferroptosis, linking it to tumor suppression and skin homeostasis.

bioRxiv · May 3, 2021 · PreprintCancer Biology

ZIP9 is a Druggable Determinant of Sex Differences in Melanoma

C. Aguirre-Portoles, R. Payne, A. Trautz, J. K. Foskett, C. A. Natale, J. T. Seykora, T. W. Ridky

The paper identifies ZIP9 as a target of testosterone in melanoma and shows that androgen receptor inhibitors can block ZIP9 to suppress melanoma growth in males.

bioRxiv · Mar 12, 2020Cancer Biology