Author

H. E. Burks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. L. Koetsier· 3 shared K. J. Green· 3 shared Q. R. Roth-Carter· 3 shared J. L. Johnson· 2 shared A. D. Ucar· 1 shared A. I. Riker· 1 shared A. L. Huffine· 1 shared B. A. Bunnell· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

J. L. Koetsier

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Author profile →

4 papers

Recent·Most cited

Crosstalk in skin: Loss of desmoglein 1 in keratinocytes inhibits BRAFV600E-induced cellular senescence in human melanocytes

X. Tong, H. E. Burks, Z. Ren, J. L. Koetsier, Q. R. Roth-Carter, K. J. Green

The paper shows that loss of desmoglein 1 in keratinocytes reduces senescence in BRAFV600E-expressing melanocytes by promoting NTN4 expression.

bioRxiv · Feb 16, 2023Cell Biology

Keratinocyte desmosomal cadherin Desmoglein 1 as a mediator and target of paracrine signaling in the melanoma niche

H. E. Burks, J. L. Pokorny, J. L. Koetsier, Q. R. Roth-Carter, C. R. Arnette, P. Gerami, J. T. Seykora, J. L. Johnson, K. J. Green

The paper shows melanoma cells exploit keratinocyte Dsg1 reduction via paracrine signaling to enhance tumor spread through CXCL1/CXCR2 and Snai2/Grhl1 pathways.

bioRxiv · Dec 1, 2022 · PreprintCancer Biology

Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

L. M. Godsel, Q. R. Roth-Carter, J. L. Koetsier, L. C. Tsoi, J. A. Broussard, G. N. Fitz, S. M. Lloyd, J. Kweon, A. L. Huffine, H. E. Burks, M. Hegazy, S. Amagai, P. W. Harms, J. L. Johnson, G. Urciuoli, , K. J. Green

This study investigates the systemic inflammatory response in Dsg1-deficient mice and humans, revealing a psoriatic-like IL-17-skewed inflammation due to genetic Dsg1 loss.

bioRxiv · Dec 1, 2020 · PreprintImmunology

Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor

T. Chang, M. D. Matossian, S. Elliot, H. E. Burks, R. A. Sabol, A. D. Ucar, H. Wathieu, J. Zabaleta, L. D. Valle, S. Gill, E. Martin, A. I. Riker, L. Miele, B. A. Bunnell, M. E. Burow, B. M. Collins-Burow

This study evaluates deacetylase inhibitors in metaplastic breast carcinoma using multiple preclinical models, finding they reduce metastasis and synergize with chemotherapy.

bioRxiv · Nov 29, 2019Cancer Biology