Author

K. K. Ito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

D. Kitagawa· 3 shared S. Hata· 3 shared T. Chinen· 3 shared K. Matsuhashi· 2 shared K. Watanabe· 2 shared A. Mabuchi· 1 shared A. Toyoda· 1 shared C. Tei· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersCell Biology

D. Kitagawa

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3 papers

Recent·Most cited

ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid cells

A. Mabuchi, S. Hata, M. Genova, C. Tei, K. K. Ito, M. Hirota, T. Komori, M. Fukuyama, T. Chinen, A. Toyoda, D. Kitagawa

This study compares ssDNA and dsDNA as HDR donors for CRISPR-mediated gene tagging in human diploid cells, finding dsDNA more efficient for precise insertion.

bioRxiv · Jun 1, 2022 · PreprintCell Biology

DONSON, a gene responsible for microcephalic primordial dwarfism, ensures proper centriole duplication cycle by maintaining centriole engagement during interphase.

K. Matsuhashi, K. Watanabe, K. K. Ito, T. Chinen, S. Hata, G. S. Stewart, D. Kitagawa

This study shows that DONSON regulates centriole duplication by maintaining centriole engagement during interphase, and its loss causes centrosome overduplication and chromosome segregation errors in MPD patient cells.

bioRxiv · May 10, 2020 · PreprintCell Biology

Cep57 and Cep57L1 cooperatively maintain centriole engagement during interphase to ensure proper centriole duplication cycle

K. K. Ito, K. Watanabe, H. Ishida, K. Matsuhashi, T. Chinen, S. Hata, D. Kitagawa

This study shows that Cep57 and Cep57L1 work together to keep centrioles engaged during interphase, preventing premature disengagement and ensuring proper centriole duplication and chromosome segregation.

bioRxiv · May 10, 2020Cell Biology