Author

A. Mabuchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:CRISPR screen· 2 Research Focus:variant calling· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Kitagawa· 3 shared M. Fukuyama· 3 shared S. Hata· 3 shared T. Chinen· 3 shared A. Toyoda· 2 shared C. Tei· 2 shared M. Genova· 2 shared T. Komori· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

D. Kitagawa

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Comprehensive analysis of end-modified long dsDNA donors in CRISPR-mediated endogenous tagging

R. Takagi, S. Hata, C. Tei, A. Mabuchi, R. Anzai, M. Fukuyama, S. Yamamoto, T. Chinen, A. Toyoda, D. Kitagawa

This study analyzes end-modified long dsDNA donors in CRISPR-mediated endogenous tagging, showing that 5 biotinylation reduces imprecise insertions and enhances HDR efficiency.

bioRxiv · Jun 28, 2024 · PreprintCell Biology

ssDNA is not superior to dsDNA as long HDR donors for CRISPR-mediated endogenous gene tagging in human diploid cells

A. Mabuchi, S. Hata, M. Genova, C. Tei, K. K. Ito, M. Hirota, T. Komori, M. Fukuyama, T. Chinen, A. Toyoda, D. Kitagawa

This study compares ssDNA and dsDNA as HDR donors for CRISPR-mediated gene tagging in human diploid cells, finding dsDNA more efficient for precise insertion.

bioRxiv · Jun 1, 2022 · PreprintCell Biology

A CRISPR-del-based pipeline for complete gene knockout in human diploid cells

T. Komori, S. Hata, A. Mabuchi, M. Genova, T. Harada, M. Fukuyama, T. Chinen, D. Kitagawa

This study introduces a CRISPR-del pipeline to achieve complete gene knockout in human diploid cells by inducing large chromosomal deletions, showing higher efficiency than conventional methods.

bioRxiv · Jun 21, 2021Cell Biology