Author

K. K. Ray

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Approach:Bayesian inference· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Assay:cryo-EM· 1 Approach:deep learning· 1

Frequent Co-Authors

C. D. Kinz-Thompson· 4 shared R. L. Gonzalez· 4 shared A. R. Verma· 1 shared B. Wang· 1 shared C. G. Altomare· 1 shared C. Wang· 1 shared G. Boël· 1 shared J. F. Hunt· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiophysics

C. D. Kinz-Thompson

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Author profile →

5 papers

Recent·Most cited

Increasing the accuracy of single-molecule data analysis using tMAVEN

A. R. Verma, K. K. Ray, M. E. Bodick, C. D. Kinz-Thompson, R. L. Gonzalez

This paper introduces tMAVEN, a software platform for analyzing single-molecule data using multiple kinetic models to improve accuracy by addressing mismatches between models and molecular mechanisms.

Biophysical Journal · Sep 1, 2024Peer-reviewedBiophysics

Biomolecular Resolution as a Quantification of Structural Information Content

C. D. Kinz-Thompson, K. K. Ray

This paper introduces a new resolution metric for structural biology that quantifies how effectively biomolecular structural information is captured across different length scales.

bioRxiv · Oct 17, 2023 · PreprintBiophysics

Cryo-EM studies of the four E. coli paralogs establish ABCF proteins as master plumbers of the peptidyl-transferase center of the ribosome

S. Singh, R. C. Gentry, Z. Fu, N. A. Bailey, C. G. Altomare, K.-H. Wong, M. J. Neky, C. Wang, K. K. Ray, Y.-C. Chi, Z. Zhang, R. A. Grassucci, J. Frank, G. Boël, R. L. Gonzalez, J. F. Hunt

This study presents cryo-EM structures of four E. coli ABCF paralogs bound to the ribosome, revealing their role in modulating tRNA geometry and catalytic function at the peptidyl-transferase center.

bioRxiv · Jun 15, 2023 · PreprintBiophysics

Entropic control of the free energy landscape of an archetypal biomolecular machine

K. K. Ray, C. D. Kinz-Thompson, J. Fei, B. Wang, Q. Lin, R. L. Gonzalez

This study reveals how ligands modulate the free energy landscape of the bacterial ribosome by altering its structural flexibility, suggesting entropic control as a general mechanism for regulating biomolecular machines.

bioRxiv · Oct 3, 2022Biophysics

Bayesian inference: The comprehensive approach to analyzing single-molecule experiments

C. D. Kinz-Thompson, K. K. Ray, R. L. Gonzalez

The paper explains how Bayesian inference provides a comprehensive framework for analyzing single-molecule experiments by rigorously accounting for uncertainties and integrating multiple experiments.

bioRxiv · Oct 23, 2020Biophysics