Author

K. Kretzschmar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

H. Clevers· 2 shared A. C. Rios· 1 shared A. Cleven· 1 shared A. D. Meringa· 1 shared A. Dohlman· 1 shared A. K. L. Wezenaar· 1 shared A. M. M. Eggermont· 1 shared C. Hsu· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

H. Clevers

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Author profile →

2 papers

Recent·Most cited

Chromatin Remodeling in Patient-Derived Colorectal Cancer Models

K. Xiang, E. Wang, G. Rupprecht, J. Mantyh, M. Negrete, G. Sanati, C. Hsu, P. Randon, A. Dohlman, K. Kretzschmar, N. Giroux, S. Ding, L. Wang, J. Prado, Q. Huang, , X. Shen

This study compares chromatin remodeling in colorectal cancer patient-derived models and identifies transcription factors driving differences in growth and drug response.

bioRxiv · Jul 24, 2022Cancer Biology

Behavioral-transcriptomic landscape of engineered T cells targeting human cancer organoids

J. F. Dekkers, M. Alieva, A. Cleven, F. Keramati, P. Brazda, H. G. Rebel, A. K. L. Wezenaar, J. Puschhof, M.-B. Buchholz, M. Barrera Roman, I. Johanna, A. D. Meringa, D. Fasci, M. H. Geurts, H. C. R. Ariese, , A. C. Rios

The paper develops BEHAV3D, a 3D imaging-transcriptomics platform to study T cell behavior and molecular mechanisms in cancer organoids, identifying a super engager cluster with unique gene signatures and IFN-I priming capabilities.

bioRxiv · May 5, 2021Cancer Biology