Author

A. D. Meringa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1

Frequent Co-Authors

J. Kuball· 2 shared Z. Sebestyen· 2 shared A. C. Rios· 1 shared A. Cleven· 1 shared A. K. L. Wezenaar· 1 shared A. M. M. Eggermont· 1 shared A. Slomp· 1 shared D. Fasci· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

J. Kuball

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Engineering BCMA CAR T cells for myeloma-targeted cargo delivery

T. Kimman, M. Cuenca, A. Slomp, R. G. Tieland, D. Rockx-Brouwer, S. Heijhuurs, A. D. Meringa, W. Boschloo, D. M. Bosma, S. Kroos, V. lo Presti, S. Nierkens, N. Bovenschen, J. Kuball, M. C. Minnema, , V. Peperzak

This paper develops BCMA CAR T cells with a granzyme B-NOXA fusion to enhance apoptosis in multiple myeloma cells, improving killing efficacy in vitro and in xenograft models.

bioRxiv · Feb 14, 2024 · PreprintImmunology

Behavioral-transcriptomic landscape of engineered T cells targeting human cancer organoids

J. F. Dekkers, M. Alieva, A. Cleven, F. Keramati, P. Brazda, H. G. Rebel, A. K. L. Wezenaar, J. Puschhof, M.-B. Buchholz, M. Barrera Roman, I. Johanna, A. D. Meringa, D. Fasci, M. H. Geurts, H. C. R. Ariese, , A. C. Rios

The paper develops BEHAV3D, a 3D imaging-transcriptomics platform to study T cell behavior and molecular mechanisms in cancer organoids, identifying a super engager cluster with unique gene signatures and IFN-I priming capabilities.

bioRxiv · May 5, 2021Cancer Biology