The BRPF1 bromodomain is a molecular reader of di-acetyllysine
J. O. Obi, M. Y. Lubula, G. Cornilescu, A. Henrickson, K. McGuire, C. M. Evans, M. Phillips, S. P. Boyson, B. Demeler, J. L. Markley, K. C. Glass
This study identifies the BRPF1 bromodomain as a selective reader of di-acetyllysine modifications on histone H4 and characterizes its binding preferences and mechanisms.
bioRxiv · Feb 13, 2020Biochemistry