Author

K. Mikkelsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

H. Ingmer· 2 shared A. Petersen· 1 shared F. S. Frisinger· 1 shared J. K. Maglegaard· 1 shared J. T. Rostoel· 1 shared J. Z. Bowring· 1 shared M. S. Tvilum· 1 shared M. Vestergaard· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

H. Ingmer

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2 papers

Recent·Most cited

Endogenous Staphylococcus aureus CRISPR-cas system limits phage proliferation and efficiently excises from the genome as part of the SCCmec cassette

K. Mikkelsen, J. Z. Bowring, Y. K. Ng, F. S. Frisinger, J. K. Maglegaard, Q. Li, R. N. Sieber, A. Petersen, P. S. Andersen, J. T. Rostoel, N. M. Hoeyland-Kroghsbo, H. Ingmer

This study shows that S. aureus CRISPR-Cas systems, located within SCCmec cassettes, limit phage proliferation but are inefficient, with phages able to escape or overload the system.

bioRxiv · Mar 19, 2023 · PreprintMicrobiology

Polyether ionophore antibiotics target drug-resistant clinical isolates, persister cells, and biofilms

M. Wollesen, K. Mikkelsen, M. S. Tvilum, M. Vestergaard, M. Wang, H. Ingmer, R. L. Meyer, T. B. Poulsen, T. Torring

This study compares nine polyether ionophores to identify those with promising antibiotic activity against drug-resistant clinical isolates, biofilms, and persister cells.

bioRxiv · Feb 13, 2023Microbiology