R. L. Meyer

Bacterial efflux pumps excrete SYTO-TM dyes from bacteria and lead to false-negative staining results

The paper shows that bacterial efflux pumps expel SYTO dyes, causing false-negative staining results in live bacterial samples.

Extracellular G-quadruplex and Z-DNA protect biofilms from DNase I and forms a DNAzyme with peroxidase activity

This study identifies non-canonical DNA structures like G-quadruplex and Z-DNA in staphylococcal biofilms that protect against DNase I and confer peroxidase activity to eDNA.

A novel high-throughput assay identifies small molecules with activity against persister cells

This paper develops a high-throughput assay to identify small molecules active against persister cells by optimizing conditions to generate high concentrations of tolerant S. aureus cells.

Polyether ionophore antibiotics target drug-resistant clinical isolates, persister cells, and biofilms

This study compares nine polyether ionophores to identify those with promising antibiotic activity against drug-resistant clinical isolates, biofilms, and persister cells.

Antibody-drug conjugates to treat bacterial biofilms

This paper develops antibody-drug conjugates that kill bacteria in biofilms and in vivo, showing superior antimicrobial effects compared to standard antibiotics.

The giant staphylococcal protein Embp facilitates colonization of surfaces through Velcro-like attachment to fibrillated fibronectin

This paper identifies Embp as a key protein in S. epidermidis that enables surface colonization by specifically binding fibrillated fibronectin through multi-valent interactions.

Novel prosthecate bacteria from the candidate phylum Acetothermia revealed by culture-independent genomics and advanced microscopy

The paper identifies a novel Acetothermia bacterium from anaerobic digesters, characterizes its genome and metabolism, and proposes a role for its unique prosthecae in nutrient uptake.