Author

K. N. Balaji

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

R. S. Rajmani· 3 shared B. Bhatt· 2 shared G. K. Lohia· 2 shared P. Prakhar· 2 shared S. M. Borbora· 2 shared N. R. Sundaresan· 1 shared S. Bhatt· 1 shared T. Mukherjee· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

9 top collaborators · 23 mutual co-author links

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3 shared papersMicrobiology

R. S. Rajmani

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Mycobacterium tuberculosis infection elevates SLIT2 expression to modulate oxidative stress responses in macrophages

S. M. Borbora, S. Bhatt, K. N. Balaji

This study shows that Mycobacterium tuberculosis infection increases SLIT2 expression in macrophages through p38/JNK pathway activation and reduced H3K27me3 repression, leading to elevated ROS levels via Vanin1.

bioRxiv · Oct 13, 2022 · PreprintMicrobiology

PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection

S. M. Borbora, R. S. Rajmani, K. N. Balaji

This paper identifies PRMT5 and YY1 as regulators of ITCH expression, which influences lipid accumulation and mycobacterial survival during infection.

bioRxiv · Nov 9, 2021Microbiology

Preexisting mycobacterial infection modulates Candida albicans-driven pyroptosis

B. Bhatt, P. Prakhar, G. K. Lohia, R. S. Rajmani, K. N. Balaji

This study shows that preexisting Mtb infection promotes C. albicans survival by modulating macrophage pyroptosis through COP1-mediated IRF9 degradation, leading to increased fungal burden and host mortality.

bioRxiv · Aug 4, 2021Microbiology

G9a and Sirtuin6 epigenetically modulate host cholesterol accumulation to facilitate mycobacterial survival

P. Prakhar, B. Bhatt, T. Mukherjee, G. K. Lohia, U. Kolthur-Seetharam, N. R. Sundaresan, R. S. Rajmani, K. N. Balaji

This study identifies G9a and Sirt6 as epigenetic regulators that modulate host cholesterol accumulation, supporting Mycobacterium tuberculosis survival.

bioRxiv · Feb 27, 2021Microbiology